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現在位置首頁>實驗試劑制品>生化試劑>分子生物學用試劑> 10127060001-β-Glucuronidase/Arylsulfatase

商品編號:72178
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10127060001-β-Glucuronidase/Arylsulfatase

價    格:771

產    地:瑞士更新時間:2019/7/15 13:41:34

品    牌:羅氏型    號:10127060001

狀    態:正常點擊量:672

13788995069
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上海嶸崴達實業有限公司

聯 系 人:runwelltac

電     話:021-64133189

傳     真:021-64129208

等     級: (第 9年)

性     質:生產型,

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?? Features and Benefits

??Deconjugate and detect both glucuronides and sulfate esters.
??Quickly screen for steroids, benzodiazepines, cannabinoids, opioids, and other drugs.

? ? Principle

Glucuronidation is one of the basic principles of metabolism. Most substances presented to the human body undergo metabolic processing that includes conjugation with glucuronic acid by UDP-glucuronosyltransferases (UGTs). This enzyme catalyzes the transfer of a glucuronyl group to many biological and pharmacologically active endogenous and exogenous molecules. Glucuronide is in general more soluble, less toxic, and more easily excreted by the human body compared to the original molecule.
In addition, sulfation of the drug or chemical substance by sulfotransferases in the human body may occur. Sulfation in general, is less predictable than glucuronidation since many isoenzymes of sulfotransferases exist, and there are individual differences in the ratio of glucuronidation versus sulfation of the substance.




產品介紹

產品描述

Working concentration: In many applications the product can be diluted with water immediately before use or employed undiluted.
Note: The present β-glucuronidase/arylsulfa

tase preparation is very concentrated and must be diluted for some applications. Moreover, in the preparation of protoplasts, the precise concentration to use for a given strain of yeast must be found empirically.
Storage conditions (working solution): Note: Aliquot portions of the diluted preparation may be stored at -15 to -25 °C; they should not be thawed and refrozen more than a time or two, and storage at the lower temperature does not lengthen their life beyond that of the product kept at 2 to 8 °C.

pecificity

?β-Glucuronidase/Arylsulfatase shows a broad specificity for many kinds of β-glucuronides and sulfate esters.


上海嶸崴達實業有限公司,專業經營生命科學領域的科研試劑、儀器和實驗室消耗品,
致力于向國內生命科學研究人員提供一流的產品和服務。?
????我們代理和經銷的分子生物學試劑、生化試劑、免疫試劑、細胞培養試劑、制藥工業原料、實驗儀器與消耗品、臨床診斷產品等,已被廣泛應用于生命科學基礎與開發研究、制藥、疾病診斷、人口與健康、生物技術等諸多領域。我們的客戶遍布大學、研究所、醫院、制藥公司、生物技術公司等單位。




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